Jian Chen

Professor

Tel: +86-51085913661

Email: jchen@jiangnan.edu.cn

Web: http://lbbe.jiangnan.edu.cn/ 

Prof. Chen received his Bachelor’s degree from Tsinghua University, master’s degree and Ph.D. from Jiangnan University (former Wuxi University of Light Industry). He was a visiting scholar at Osaka University, Tokyo Institute of Technology and Inha University. Currently, he is the Professor of School of Biotechnology in Jiangnan University. He is the Chief Editor of Food Bioscience, and serves on the Board of Editors for Process Biochemistry. He also honored International Academy of Food Science and Technology Fellow (IAFoST Fellow) and Fellow of International Bioprocessing Association (FIBA). 

Prof. Chen’s group focuses on solving key scientific and engineering problems in fermentation engineering to realize efficient fermentation process with high titer, high yield, and high productivity. Systems and methods of microbial cell factories construction in combination with theories and technologies of fermentation process were intensively investigated by Prof. Chen’s group.

Prof. Chen has published more than 500 original/review papers in academic journals, including leading journals his area, such as Nature Communication, Biotechnology Advances, and Metabolic Engineering. He was honored with National Science and Technology Award, National Technology Invention Awards, Ho Leung Ho Lee Science and Technology Innovation Award-Industrial Innovation Award, Golden Award of Chinese Patent, National Outstanding Young Investigator, Chief Scientist of the Major State Basic Research Development Program of China.

1) Yanfeng Liu, Hannes Link, Long Liu, Guocheng Du, Jian Chen, Uwe Sauer. A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine overproducing Bacillus subtilis Nature Communications 2016. 7:11933 (2016 IF=12.124)

2) Xian Yin, Jianghua Li, Hyun-dong Shin, Guoheng Du, Long Liu, Jian Chen. Metabolic engineering in the biotechnological production of organic acids in the tricarboxylic acid cycle of microorganisms: Advances and prospects Biotechnology Advances 2015. 33: 830-841 (2016 IF=10.597)

3) Jingwen Zhou, Guocheng Du, Jian Chen. Novel fermentation processes for manufacturing plant natural products Current Opinion in Biotechnology 2014. 25: 17-23 (2016 IF=9.294)

4) Peng Jin, Zhen Kang, Panhong Yuan, Guocheng Du, Jian Chen. Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis 168 Metabolic Engineering 2016. 35:21-30 (2016 IF=8.142)

5) Peng Jin, Wenwen Ding, Guocheng Du, Jian Chen, Zhen Kang. DATEL: A scarless and sequence-independent DNA assembly method using thermostable exonucleases and ligase ACS Synthetic Biology 2016. 5(9):1028-1032 (2016 IF=5.382)

6) Ningzi Guan, Jianghua Li, Hyun-dong Shin, Guocheng Du, Jian Chen, Long Liu. Metabolic engineering of acid resistance elements to improve acid resistance and propionic acid production of Propionibacterium jensenii Biotechnology and Bioengineering 2016.113: 1294-1304 (2016 IF=4.481)

7) Junjun Wu, Guocheng Du, Jingwen Zhou, Jian Chen. Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy Metabolic Engineering 2013, 16:48-55 (2016 IF=8.142)

8) Lili Gao, Yudong Hu, Jie Liu, Guocheng Du, Jingwen Zhou, Jian Chen. Stepwise metabolic engineering of Gluconobacter oxydans WSH-003 for the direct production of 2-keto-L-gulonic acid from D-sorbitol Metabolic Engineering 2014, 24: 30-37 (2016 IF=8.142)

9) Haiquan Yang, Xinyao Lu, Long Liu, Hyun-dong Shin, Rachel R Chen, Jianghua Li, Guocheng Du, Jian Chen. Fusion of an oligopeptide to the N terminus of an alkaline - amylase from Alkalimonas amylolytica simultaneously improves the enzyme’s catalytic efficiency, thermal stability, and resistance to oxidation Applied and Environmental Microbiology 2013, 79: 3049-3058 (2016 IF=3.807)

10) Xinrui Zhao, Guocheng Du, Huijun Zou, Jianwei Fu, Jingwen Zhou, Jian Chen. Metabolic engineering of the regulators in nitrogen catabolite repression to reduce the production of ethyl carbamate in a model rice wine system Applied and Environmental Microbiology 2014, 80(1): 392-398 (2016 IF=3.807)