Professor

Tel: 86-510-85918167

Email: xbyu@jiangnan.edu.cn

Web:

2005 – Present    Professor,   Jiangnan University, School of Biotechnology.

1998 – 2005      Associate professor,   Jiangnan University, School of Biotechnology.

1994 –1998      Lecture,   Wuxi University of  Light  Industry

1997-1998          Postdoctoral Fellow, Inha  University, Korea

1990 – 1994        Ph.D   Fellow, Wuxi University of  Light  Industry

1987 – 1990          M.Sc. , Wuxi Institute of Light  Industry 

1981 – 1985          B.Sc., Nanjing University

Main research   interesting on the two area, Health fermented food and enzyme technology,

Health   fermented food including:

1.    Various fruit   wine, rice wine, soy sauce and vinegar, the spirit of   Low degree of drunkenness, fermented beverage、fermented tea, discover function microbial and promotion   functional components.

2.    microorganism and enzyme are used for high value conversion of  plant/vegetables   and fruits /cereal/Chinese herbal medicine; such as excision or connection of   glycosides, Saponins transformation，the promotion of three terpenoids compounds, Water-soluble   transformation of ester soluble components by  fermentation, Getting   better functional ingredients and improving the bioavailability of functional   components.

3.    Selection of probiotics, identification of functional and food   use.

4.    The production of food functional factors by microbial fermentation.

5.    The development of  fermented food therapy products for the   treatment and prevention of various disease （antitumor, antihypertensive, hypolipidemic,   hypoglycemic, Prevention of gou etc.）.

Development and application of enzyme   preparation

1、  Discovery new type enzyme and Construction of high yield   gene  recombinant Pichia pastoris

2、  Enzyme application technology

1.FANG Lei;CHEN Hong; YU Xiao-bin  “Isolation   of high-conversion ginsenoside strain and optimization of fermentation medium”     Food and Fermentation Industries  2017,43(4):147-151

2. CHEN Hong,FANG Lei,YU Xiao-bin “Influence of different cultivation methods on   ganoderic acid synthesis and solid-state fermentation condition optimization”   Science and Technology of Food Industry, 2017,38(11):167-172

3. GUO Xiao-xu, YUAN Zhao-qi, LI Guo-ying, YU   Xiao-bin “Study on cultivation conditions for pure   red starter with high-yielding monacolin K”Industrial   Microbiology  2016,1:27-30

4. FENG Lingran;WANG Qiang;LUO Wei;YU Xiaobin “Screening and Identification of Strains with Tea   Polyphenols Conversion Activity in Pu-erh Tea Samples”Journal of Food Science and Biotechnology  2014,7:1673-1689

5. PEI Min;WANG Qiang;LUO Wei;GU Qiu-ya;GONG   Zun-yang;YU Xiao-bin “Breeding of lycopene   high producing strain by N+ implantation and analysis of gene transcription”Food and Fermentation Industries  2015,11:70-75

6. LIU Hu-jun;LUO Wei;FAN Xin-lei;YU Xiao-bin “Cloning and Heterologous Expression of Glucose Oxidase   Gene from Aspergillus niger PCTC in Pichia pastoris”2013,6:615-621

7. WANG Shenqiang;LUO Wei;JIANG Yitong;YU Xiaobin   “Enhancing DHA synthesis in Schizochytrium limacinum   by exogenous additives”Chinese Journal of Bioprocess   Engineering   2013,5:21-25

8. SUN Xiaowei;WANG Qiang;YU Xiaobin “Optimization of the Fermenting Techniques of Sweet   Blackcurrant Wine 

Liquor-Making Science & Technology”  2015,4:81-91

9. Liu Xiaobo， Luo Wei，   Gu Qiuya， Yu   Xiaobin “Multi-repeat   stress acclimation and butanol high-yielding strain screening by multi-factor   complex medium ” Microbiology China  2012,11:1629-1635

10.Minghai  Hana,  Xinfeng    Wang,  Huaiyu  Ding,  Mingyi  Jin,  Lingang    Yu,  Junlei  Wangb,Xiaobin  Yu

“The  role    of  N-glycosylation  sites  in  the  activity,    stability,  and expression  of  the  recombinant    elastase  expressed  by  Pichia  pastoris”Enzyme  and  Microbial    Technology  2014 ,54: 32– 37

11.Minghai  Hana, Huaiyu  Ding,    Junlei  Wang,  Mingyi  Jin,  Xiaobin  Yu,“Expression  of  the  lasB    gene  encoding  an  organic  solvent-stable elastase    in  Pichia  pastoris  and  potential    applications  of  the recombinant  enzymes  in    peptide  synthesis”  Biochemical  Engineering    Journal  77 (2013) 154–  160

12.Xiao-Bo Liu, Qiu-Ya Gu, Xiao-Bin Yu “Repetitive domestication to enhance butanol tolerance   and production in Clostridium acetobutylicum through artificial   simulation of bio-evolution”Bioresource Technology   2013,130: 638–643

13.Han-guang Li, Wei Luo, Qiu-ya Gu, Qiang Wang,   Wen-jun Hu, Xiao-bin Yu“Acetone, butanol, and ethanol production   from cane molasses using Clostridium beijerinckiimutant obtained by combined   low-energy ion beam implantation andN-methyl-N-nitro-N-nitrosoguanidine induction”Bioresource Technology 2013，137：254–260

14.Han-guang Li,  Qiu-ya Gu, Qiang Wang, Wen-jun   Hu, Xiao-bin Yu “Acetone, butanol, and ethanol production   from gelatinized cassava flour by a new isolates with high butanol tolerance”Bioresource Technology 172 (2014) 276–282

15. Qiang Wang, Ling-ran Feng, Wei Luo,Han-guang Li,Ya   Zhou, Xiao-bin Yu “Effect of Inoculation Process on Lycopene   Production by Blakeslea trispora in a Stirred-Tank Reactor”Appl Biochem Biotechnol 2015, 175:770–779

16. Guo-YingLi,Zhang-CaiLuo,YUAN Fan, Xiao-bin Yu“Combined process of high-pressure homogenization and   hydrothermal extraction for the extraction of fucoidan with good antioxidant   properties from Nemacystus decipients”Food and   Bioproducts Processing  2017,106:35-42

17. Xiao-bin Yu “Production   of Cellulase  by Trichoderma reesei Rut C30  in  Wheat-Bran   Containing Media.”J. Microbiol. Biotechnol.   1998,8(3),208-213

18. Xiao-bin Yu “Cellulase   Production in Fed-Batch Culture by Trichoderma   reesei Rut C30.”J. Microbiol. Biotechnol. 1999,9(1),44-49.