Professor

Tel: (86)510-85918156

Email: zhengpu@jiangnan.edu.cn

Web:

2009 – present    Professor, Jiangnan   University, School of Biotechnology

2003 – 2009       Associate   Professor, Jiangnan University

2000 – 2003      Associate   research fellow, Jiangsu institute of microbiology

1991 – 2000       Technician,   Jiangsu institute of microbiology

2008 – 2014      Ph.D.,   Jiangnan University

1988 – 1990      M.ESc.,Tianjin   University of Science and Technology

1984 – 1988      B.Eng.,   Zhejiang University of Technology                             

Focusing on   industrial biotechnology, our group is interested in the new technology and   theory in the fields of biocatalysis and biorefinery. The main research scope   includes:

(1) Breeding   and modification of industrial microorganisms: high-throughput screening strategy   used in wild-type strains, genome shuffling technology for breeding excellent   strains, and strain construction by genetic engineering strategy based on the   principles of  metabolic engineering and enzymatic catalysis.

 (2)   Cell and enzyme immobilization: developing magnetic immobilized enzymes,   enzymes with reversible solubility and carrier free cross-linked enzyme   aggregates to suit the heterogeneous and non-aqueous reaction systems,   adsorption and fermentation techniques of living cells on various carrier   materials, and construction of corresponding reactors.

(3)   Biorefinery of bio-based chemicals and fragrance ingredients: fermentative production   of bulk chemicals (succinic acid) with renewable resources such as straw,   distillers’ grains and bagasse; also, processing methods of   raw materials, mechanisms of simultaneous saccharification & fermentation   and separate hydrolysis & fermentation techniques, products extraction,   and the bottleneck of the industrialization process are also studied.

1.       Zhao   Ming-Tao, Zheng Pu*, Peng-Cheng Chen, Liu Si-Qin. Biosynthesis of heliotropin   by a novel strain of serratia liquefaciens. Applied Biochemistry and   Biotechnology, 2017, 10.1007/s12010-017-2497-1.

2.       Peng-Cheng   Chen, Zha Xin-hua, Zheng Pu*. Construction of fibrous bed bioreactor for   enhanced succinic acid production using wastewater of dextran fermentation.   Bioprocess and Biosystems Engineering. 2017, 40, 1859-1866.

3.       Peng-Cheng   Chen, Pu Zheng*, Xiang-Yu Ye, Fan Ji. Preparation of A. succinogenes immobilized   microfiber membrane for repeated production of succinic acid. Enzyme and   Microbial Technology, 2017, 98, 34–42.

4.       Peng-Cheng   Chen, Sheng-Tao Tao, Pu Zheng*. Efficient and repeated production of succinic   acid by turning sugarcane bagasse into sugar and support. Bioresource   Technology, 2016, 211, 406–413.

5.       Peng-Cheng   Chen, Pu Zheng*, Qun Zhang. Commentary on succinic acid and poly-g-glutamic acid production   using lignocellulosic waste biomass. Research & Reviews: Journal of   Microbiology and Biotechnology, 2016, 4, 11-13.

6.       Wei Liu, Pu   Zheng*, Fang Yu, Qian Yang. A two-stage process for succinate production   using genetically engineered Corynebacterium acetoacidophilum. Process   Chemistry, 2015, 50,1692–1700.

7.       Jie Wang, Pu   Zheng*， Muconic acid   production from glucose using enterobactin precursors in Escherichia coli.   Journal of Industrial Microbiology and Biotechnology, 2015, 42, 701-709.

8.       Bo Hua Gu, Pu   Zheng*, Qiang Yan, Wei Liu. Aqueous two-phase system: An alternative process   for recovery of succinic acid from fermentation broth. Separation and   Purification Technology, 2014, 138, 47-54.

9.       Qiang Yan, Pu   Zheng*, Jin-Jun Dong, Zhi-Hao Sun. A Fibrous bed bioreactor to improve the   productivity of succinic acid by Actinobacillus succinogenes. Journal   of Chemical Technology and Biotechnology, 2014, 89, 1760-1766.

10.     Qiang Yan, Pu   Zheng*,Sheng-Tao Tao, Jin-Jun Dong. Fermentation process for continuous production   of succinic acid in a fibrous bed bioreactor. Biochemical Engineering Journal,   2014, 91, 92-98.

11.     Pu Zheng*,   Kun Zheng, Qiang Yan, Yan Xu*, Zhi-Hao Sun. Enhanced succinic acid production   by Actinobacillus succinogenes after genome shuffling. Journal of   Industrial Microbiology and Biotechnology, 2013, 40, 831-840.

12.     Pu Zheng*,   Jie Wang, Chan Lu, Yan Xu*, Zhi-Hao Sun. Immobilized β-glucosidase on magnetic   chitosan microspheres for hydrolysis of straw cellulose. Process   Biochemistry, 2013, 48, 683-687.

13.     Xiao-Bin   Zhou, Pu Zheng*. Spirit-based distillers’grain as a promising raw material for succinic acid   production. Biotechnology Letters, 2013, 35, 679-684.

14.     Xu’e Yang, Pu Zheng*, Ye   Ni, Zhi-Hao Sun. Highly efficient biosynthesis of sucrose-6-acetate with   cross-linked aggregates of Lipozyme TL 100 L. Journal of Biotechnology, 2012,   161, 27-33.

15.     Pu Zheng*,   Miao Liu, Xiao-De Liu, Qiao-Yan Du, Ye Ni, Zhi-Hao Sun* Genome shuffling   improves thermotolerance and glutamic acid production of Corynebacteria   glutamicum, World J Microbiol Biotechnol, 2012, 28, 1035–1043

16.     Pu Zheng, Hui   Li, Xinglin Wang, Haijian Zhou, Shibiao Zhu. An Amycolatopsis sp. Strain and   Methods of Using the Same for Vanillin Production. US9115377B2