Professor

Tel: 86510-85918307

Email: zkang@jiangnan.edu.cn

Web:

2011 – present    Associate professor,   Jiangnan University, School of Biotechnology

2015 – 2016       Visiting   research fellow, University of Illinois at Urbana-Champaign

2006 – 2011       M.Sc. and   Ph.D., Shandong University

2002 – 2006       B.Sc., Laiyang   agricultural university

The research   mainly focused on synthetic biology and metabolic engineering. We devoted to   develop novel molecular biological methods and approaches to rapid   engineering enzymes and synthetic circuits and pathways. To date, I have   published more than 40 peer-reviewed papers (as first author or corresponding   author) on Metabolic Engineering, ACS Synthetic Biology, Applied   Environmental Microbiology, Carbohydrate Polymers, Scientific Reports,   Biotechnology Advances. I am the Editorial members of the journal of Biotechnology   Letters, Frontiers in Synthetic Biology, and Frontiers in Process and   Industrial Biotechnology.

1. Yang S, Liu Q, Zhang Y, Du G, Chen J,   Kang Z*. 2017. Construction and Characterization of Broad-Spectrum   Promoters for Synthetic Biology. ACS Synth Biol. doi:   10.1021/acssynbio.7b00258.

2. Zhang Y, Huang H, Yao X, Du G, Chen J, Kang   Z*. 2017. High-yield secretory production of stable, active trypsin   through engineering of the N-terminal peptide and self-degradation sites in   Pichia pastoris. Bioresour Technol. 247:81-87.

3. Liu Q, Chen Y, Yuan M, Du G, Chen J, Kang   Z*. 2017. A Bacillus paralicheniformis Iron-Containing Urease Reduces   Urea Concentrations in Rice Wine. Appl Environ Microbiol. 83(17).

4. Jin P, Kang Z*, et al. 2016.   Production of specific-molecular-weight hyaluronan by metabolically   engineered Bacillus subtilis 168. Metab Eng. 35:21-30.

5. Jin, P, Kang Z*, et al. 2016.   DATEL: A Scarless and Sequence-Independent DNA Assembly Method Using   Thermostable Exonucleases and Ligase. ACS Synth Biol. 5:1028-1032.

6. Jin, P., Kang Z*, Zhang, J.,   Zhang, L., Du, G., & Chen, J. 2016. Combinatorial evolution of enzymes   and synthetic pathways using one-step PCR. ACS Synth Biol. 5: 259-268.

7. Zhang Y, Ling Z, Kang Z*, et al.   2016. Development of a novel auto-catalyzed strategy for improving trypsin   production in Pichia pastoris. Sci Rep 6: 23158.

8. Zhang J, Kang Z*, et al. 2015.   Optimization of the heme biosynthesis pathway for the production of   5-aminolevulinic acid in Escherichia coli. Sci Rep. 5: 8584.

9. Jin P, Kang Z*, et al. 2014.   High-yield novel leech hyaluronidase to expedite the preparation of specific   hyaluronan oligomers. Sci Rep. 4: 4471.

10. Ling Z, Liu Y, Teng S, Kang Z*,   et al. 2013. Rational design of a novel propeptide for improving active   production of Streptomyces griseus trypsin in Pichia pastoris. Appl Environ   Microbiol. 79: 3851-55.

11. Jin P, Zhang L, Yuan P, Kang Z*,   et al. 2016. Efficient biosynthesis of polysaccharides chondroitin and   heparosan by metabolically engineered Bacillus subtilis. Carbohydr Polym.   140: 424-432.

12. Yuan P, Lv M, Jin P, Wang M, Du G, Chen   J, Kang Z*. 2015. Enzymatic production of specifically distributed   hyaluronan oligosaccharides. Carbohydr Polym. 129: 194-200.

13. Zhang J, Kang Z*, et al. 2013.   High-level extracellular production of alkaline polygalacturonate lyase in   Bacillus subtilis with optimized regulatory elements. Bioresource Technol.   146: 543-48.

14. Yang S, Du G, Chen J, Kang Z*.   2017. Characterization and application of endogenous phase-dependent   promoters in Bacillus subtilis. Appl Microbiol Biotechnol. 101(10):4151-4161.

15. Yang Y, Kang Z*, et al. 2015.   High-level expression and characterization of recombinant acid urease for   enzymatic degradation of urea in rice wine. Appl Microbiolo Biotechnol. 99:   301-8.

16. Kang Z, et al. 2012. Recent   advances in microbial production of δ-aminolevulinic acid and vitamin B12.   Biotechnol Adv. 30: 1533-42.

17. Kang Z, et al. 2011. Engineering   Escherichia coli for efficient production of 5-aminolevulinic acid from   glucose. Metab Eng. 13: 492-498.

18. Kang Z, et al. 2011. Production   of succinate and polyhydroxyalkanoate from substrate mixture by metabolically   engineered Escherichia coli. Bioresource Technol. 102: 6600-04. 

19. Kang Z, et al. 2010. A novel   strategy for succinate and polyhydroxybutyrate co-production in Escherichia   coli. Bioresource Technol. 101: 7675-78.

21. Kang Z*, et al. 2016. Enhanced   production of leech hyaluronidase by optimizing secretion and cultivation in   Pichia pastoris. Appl Microbiol Biotechnol. 100: 707-17.

22. Kang Z*, et al. 2014. Small RNA   regulators in bacteria: powerful tools for metabolic engineering and   synthetic biology, Appl Microbiol Biotechnol. 98: 3413-24.

23. Kang Z, et al. 2008.   Construction of a stress-induced system in Escherichia coli for efficient   polyhydroxyalkanoates production. Appl Microbiol Biotechnol. 79: 203-08.