Associate Professor

Tel:+86051085326829

Email:yuxin@jiangnan.edu.cn;marshalxy@gmail.com;   marshalxy@hotmail.com

Web:

2009 – present   Associate Professor,   Jiannan University, School of Biotechnology

2014 – 2015      Visiting   Scholar, University of Minnesota, Institute of Biotechnology

2004 – 2009      Ph.D., Shanghai   Jiaotong University

2000 – 2004      B.Sc., Shanghai   Jiaotong University

Xin’s work is   focused on enzyme engineering and macro-molecule interaction.

1.   Jun Shao, Ying Yin, Xiaowen Yina, Li Jia, Yu Xin*, Jian Zouc*, Yong   Yao*, Transthyretin exerts pro-apoptotic effects in human retinal   microvascular endothelial cells through a GRP78-dependent pathway in diabetic   retinopathy. Cellular Physiology and Biochemistry 2017

,   43, 788-800. (IF 5.104)

2.   Yu Xin，Mengling Zheng，Qing   Wang，Liushen Lu，Ling   Zhang，Yanjun Tong，Wu   Wang，Structural and catalytic alteration of   sarcosine oxidase through reconstruction with coenzyme-like ligands，Journal   of Molecular Catalysis B: Enzymatic 2016, 133, s250-258 (IF 2.269)

3.   Yu Xin，Liushen Lu，Qing   Wang，Ling Zhang，Yanjun   Tong，Wu Wang，Coenzyme-like   ligands for affinity isolation of cholesterol oxidase，Journal   of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences，2016.01.29，1021：169-174.   (IF 2.603)

4.   Xin Y., Liu L.H., Chen B.Z., Zhang L., Tong Y.J., Affinity   purification of aprotinin from bovine lung. J. Sep. Sci. 2015, 38, 1441–1448.   (IF 2.557)

5.   Xin Y., Yang H.L., Xia X.L., Zhang L., Cheng C., Mou G.C., Shi J.B.,   Han Y.F., Wang W., Affinity purification of a cholesterol oxidase expressed   in Escherichia coli. J Chromatogr B, 2011, 879, 853–858. (IF 2.603)

6.   Xin Y., Yang H.L., Xia X.L., Zhang L., Zhang Y.R., Tong Y.J., Wang W.,   Preparation and characterization of affinity sorbents based on   isoalloxazine-like ligands for separation of flavoenzymes. J. Sep. Sci. 2011,   34, 2940–2949. (IF 2.557)

7.   Xin Y., Yang H.L., Xia X.L., Zhang L., Zhang Y.R., Cheng C., Wang W.,   Expression, purification and partial characterization of a xanthine oxidase   (XOD) in Arthrobacter sp.. Process Biochem 2012, 47, 1539-1544. (IF 2.497)

8.   Xin Y., Yang H.L., Xia X.L., Zhang L., Zhang Y.R., Tong Y.J., Chen Y.,   Wang W.,

Expression   and comparison of recombinant cholesterol oxidases (COD) in Escherichia coli   with native cholesterol oxidase expressed in Brevibacterium sp.. Afr J   Biotechnol, 2011, 10(66), 14968-14976.

9.   Xin Y., Yang H.L., Xia X.L., Zhang L., Zhang Y.R., Tong Y.J., Chen Y.,   Wang W.,

Affinity   purification of urinary trypsin inhibitor from human urine. J. Sep. Sci.   2012, 35, 1–6. (IF 2.557)

10.   Tong Y.J., Xin Y., Yang H.L., Zhang L., Zhang Y.R., Chen Y., Xia X.L.,   Wang W.,

Preparation   and Performance Research on Glutathione Molecularly Imprinted Polymers. Chromatographia,   2011, 74, 443–450. (IF 1.402)

11.   Xin Y., Tong Y.J., Yang H.L., Zhang L., Zhang Y.R., Chen Y., Wang W.,   Study on the Glutathione Molecularly Imprinted Polymers with different   functional monomers. Acta Chim. Sinica. 2012, 70 (6), 803-811. (IF 2.131)

12.   Shao J., Xin Y., Li R.X., Fan Y., Vitreous and serum levels of   transthyretin (TTR) in high myopia patients are correlated with ocular   pathologies. Clin. Biochem., 2011 44, 681-685. (contributed equally with first author) (IF 2.434)

13.   Shao J., Xin Y., Yao Y., Correlation of misfolded transthyretin in   abnormal vitreous and high myopia related ocular pathologies. Clin. Chim.   Acta., 2011, 412, 2117-2121. (contributed equally with first author) (IF 2.871)

14.   Xin Y., Dong D.X., Wang T., Li R.X., Affinity purification of serine   proteinase from Deinagkistrodon acutus venom. J Chromatogr B, 2007, 859 (1),   111-118. (IF 2.603)

15.   Xin Y., Dong D.X., Chen D.Z., Li R.X., Structural and biological   characterization of a novel acutobinlike enzyme isolated from the venom of   the sharp-nosed pit viper

(Deinagkistrodon   acutus). Biotechnol. Appl. Biochem., 2009, 53, 123-131. (IF 1.413)

16.   Shao J., Xin Y., Yao Y., Zhu J., Functional analysis of misfolded   transthyretin extracted from abnormal vitreous with high myopia related   ocular pathologies. Clin. Chim. Acta., 2012, 415, 20-24 . (contributed equally with   first author)   (IF 2.871)

17.   Yanjun Tong, Yu Xin, Hailin Yang, Ling Zhang, Xiumei Tao, Hui Xu, Wu   Wang, Novel affinity purification of monomeric sarcosine oxidase expressed in   Escherichia coli. J. Sep. Sci. 2013, 36, 3086–3092. (IF 2.557)

18.   Yuran Zhang, Yu Xin, Hailin Yang, Ling Zhang, Xiaole Xia, Yanjun Tong,   Yi Chen, Wu Wang, Thermal inactivation of xanthine oxidase from Arthrobacter   M3:

mechanism   and the corresponding thermostabilization strategy. Bioprocess Biosyst Eng DOI   10.1007/s00449-013-1042-z (IF 1.870)

19.   Yi Chen,Yu Xin, Hailin Yang, Ling Zhang, Yuran Zhang, Xiaole Xia,   Yanjun Tong, Wu Wang, Immobilization and stabilization of cholesterol oxidase   on modified

sepharose   particles. International Journal of Biological Macromolecules 56 (2013) 6–   13. (IF 3.671)