Associate Professor

Tel: 86-510-85918299

Email: jmgao@jiangnan.edu.cn

Web:

2015-present:   Associate Professor, School of   Biotechnology, Jiangnan University

2012-2015: Assistant   Professor, School of Biotechnology, Jiangnan University

2005-2012:   Ph. D, Fermentation Engineering, Jiangnan University

1999-2003:   Bachelor of Engineering, Biological Engineering, Jiangnan University

1.      Bioreactor   and bioprocess control system design and simulation for aerobic fermentation,   specifically, high density and high viscosity system.

2.      Intelligent   control and systems analysis of the recombinant proteins expression process   by Pichia pastoris.

3.        Biotransformation and biocatalysis for   oligosaccharides and polysaccharides synthesis.

1.      Jian Ding, Lu-qiang Jia, Enock   Mpofu, Min-Jie Gao^*, Xi-dong Ren^*. An on-line adaptive glucose feeding system incorporating   patterns recognition for glucose concentration control in glutamate   fermentations，Biotechnology and   Bioprocess Engineering，2016, 21(6): 758-766.

2.        Min-Jie Gao,   Cheng Wang, Zhi-Yong Zheng, Li Zhu, Xiao-Bei Zhan, Chi-Chung Lin. Improving   arachidonic acid fermentation by Mortierella alpina   through multi-Stage temperature and aeration rate control in bioreactor. Preparative   Biochemistry and Biotechnology, 2016, 46(4):360-367.

3.        Min-Jie Gao, Xiao-Bei Zhan, Peng   Gao, Xu Zhang, Shi-Juan Dong, Zhen Li, Zhong-Ping Shi, Chi-Chung Lin. Improving   performance and operational stability of porcine interferon-α production by Pichia   pastoris with combinational induction strategy of low temperature and   methanol/sorbitol co-feeding. Applied Biochemistry and   Biotechnology, 2015, 176(2): 493-504.

4.        Min-Jie Gao, Zhong-Ping Shi.   Process control and optimization for heterologous protein productions by   methylotrophic Pichia pastoris. Chinese Journal of Chemical   Engineering, 2013, 21(2): 216-226.

5.         Min-Jie Gao, Xiao-Bei Zhan, Zhi-Yong Zheng, Jian-Rong Wu, Shi-Juan   Dong, Zhen Li, Zhong-Ping Shi, Chi-Chung Lin. Enhancing pIFN-α production and   process stability in fed-batch culture of Pichia pastoris by   controlling the methanol concentration and monitoring the responses of OUR/DO   levels. Applied Biochemistry and Biotechnology, 2013, 171:   1262-1275.

6.         Min-Jie Gao, Zhi-Yong Zheng, Jian-Rong Wu, Shi-Juan Dong, Zhen Li, Hu Jin, Xiao-Bei Zhan, Chi-Chung Lin.   Improvement of specific growth rate of Pichia pastoris for effective   porcine interferon-α production with an on-line model   based glycerol feeding strategy. Applied   Microbiology and Biotechnology, 2012, 93(4): 1437-1445.

7.        Min-Jie Gao, Zhen Li, Rui-Song   Yu, Jian-Rong Wu,   Zhi-Yong Zheng, Zhong-Ping Shi, Xiao-Bei Zhan, Chi-Chung Lin. Methanol/sorbitol   co-feeding induction enhanced porcine interferon-α production by P.   pastoris associated with energy metabolism shift. Bioprocess and   Biosystems Engineering, 2012, 35(7): 1125-1136.

8.         Min-Jie Gao, Shi-Juan Dong, Rui-Song Yu, Jian-Rong Wu, Zhi-Yong Zheng,   Zhong-Ping Shi, Xiao-Bei Zhan. Improvement of ATP regeneration   efficiency and operation stability in porcine interferon-α production by Pichia   pastoris under lower induction temperature. Korean Journal of   Chemical Engineering, 2011, 28(6): 1412-1419.

9.        Ying Liang, Li Zhu, Han Ding, Min-Jie Gao, Zhi-Yong Zheng, Jian-Rong Wu, Xiao-Bei Zhan. Enhanced   production of curdlan by coupled fermentation system of Agrobacterium sp.   ATCC 31749 and Trichoderma harzianum GIM 3.442. Carbohydrate Polymers,   2017, 157: 1687-1694.

10.    Jian Ding, Min-Jie Gao, Guo-Li Hou,   Ke-Xue Liang. Effect of ethanol accumulation on porcine   interferon-α production by Pichia pastoris and activities of key   enzymes in carbon metabolism. Applied Biochemistry and Biotechnology,   2015, 176:1964-1974.

11.  Jian Ding, Min-jie Gao, Guo-li Hou, Ke-xue Liang,   Rui-song Yu,   Zhen Li, Zhong-ping Shi.   Stabilizing porcine interferon-α production by Pichia pastoris with an   ethanol on-line measurement based DO-Stat glycerol feeding strategy. Journal of Chemical   Technology & Biotechnology, 2014, 89(12): 1948-1953.

12.  Jian Ding, Chun-ling Zhang,   Min-jie Gao, Guo-li Hou, Ke-xue Liang, Chun-hua Li,   Jian-ping Ni,   Zhen Li, Zhong-ping Shi.   Enhanced porcine circovirus Cap protein production by Pichia pastoris   with a fuzzy logic DO control based methanol/sorbitol co-feeding induction   strategy. Journal of Biotechnology, 2014, 177: 35-44.

13.  Li-Bo Yang, Xiao-Bei Zhan, Zhi-Yong Zheng, Jian-Rong Wu, Min-Jie   Gao, Chi-Chung Lin. A novel osmotic pressure control fed-batch   fermentation strategy for improvement of erythritol production by Yarrowia   lipolytica from glycerol. Bioresource Technology, 2014,   151: 120-127.

14.  Hu Jin,   Zhi-Yong Zheng, Min-Jie Gao, Zuo-Ying Duan, Zhong-Ping Shi,   Zheng-Xiang Wang, Jian Jin. Effective induction of phytase in Pichia   pastoris fed-batch culture using an ANN pattern recognition model based   on-line adaptive control strategy. Biochemical Engineering Journal,   2007, 37: 26-33.