Associate Professor

Tel: +86-51085918307

Email: yanfengliu@jiangnan.edu.cn

Web: http://lbbe.jiangnan.edu.cn/cn/index.php

Dr. Yanfeng Liu focuses on microbial   metabolic engineering and systems biology for efficient synthesis of   nutraceutically important and cosmetically useful biochemicals. Specifically,   systems biology, computational biology, and systems metabolic engineering   approaches were developed and applied to identify and eliminate rate-limiting   steps in biosynthesis of nutraceuticals and biochemicals, such as N-acetylneuraminic   acid and ceramide. Fermentation process optimization is combined with   microbial cell factories construction for improved target compound   production.  

Dr. Liu has authored 14 papers including   review and research papers published on peer-reviewed journals, including   leading journals in his area, such as Nature Communications, Biotechnology   Advances, and Metabolic Engineering, etc. He has won the Best Paper Award of   the 7^th International Forum on Industrial Bioprocesses (2017).

1.       Liu Y., Link H., Liu L., et al.,   2016. A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine   overproducing Bacillus subtilis. Nature Communications. 7,   11933. (2016 IF=12.124)

2.       Liu Y., Li J., Du G., et al.,   2017. Metabolic engineering of Bacillus subtilis fueled by systems   biology: Recent advances and future directions. Biotechnology Advances. 35, 20-30. (2016 IF=10.597)

3.       Liu Y., Zhu Y., Ma W., et al.,   2014. Spatial modulation of key pathway enzymes by   DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine   production by Bacillus subtilis. Metabolic Engineering. 24,   61-69. (2016 IF=8.142)

4.         Liu   Y., Zhu Y., Li J., et al.,   2014. Modular pathway engineering of Bacillus subtilis for improved N-acetylglucosamine   production. Metabolic Engineering. 23, 42-52. (2016 IF=8.142)

5.         Liu   Y.,   Liu L., Shin H.-d., et al., 2013. Pathway engineering of Bacillus subtilis for   microbial production of N-acetylglucosamine. Metabolic   Engineering. 19:107-115. (2016 IF=8.142)

6.         Liu   Y.,   Shin H.-d., Li J., et   al., 2015. Toward metabolic engineering in the context of system   biology and synthetic biology: advances and prospects. Applied   Microbiology and Biotechnology. 99, 1109-1118. (2016 IF=3.420)

7.         Liu L.^#,   Liu Y.^# (Co-first author), Shin   H.-d., et al., 2013. Developing   Bacillus spp. as a cell factory for production of microbial enzymes   and industrially important biochemicals in the context of systems and   synthetic biology. Applied Microbiology and Biotechnology. 97,   6113-6127. (2016 IF=3.420)

8.         Liu L.^#,   Liu Y.^# (Co-first author), Shin H.-d., ,   et al., 2013. Microbial   production of glucosamine and N-acetylglucosamine: advances and   perspectives. Applied Microbiology and Biotechnology. 97,   6149-6158. (2016 IF=3.420)

9.         Zhu Y.,   Liu Y., Li J., et al., 2015. An optimal glucose feeding strategy integrated with   step-wise regulation of the dissolved oxygen level improves N-acetylglucosamine   production in recombinant Bacillus subtilis. Bioresource   Technology. 177, 387–392. (2016 IF=5.651)

10.     Liu L.,   Liu Y., Li J., et al., 2011. Microbial production of hyaluronic acid: current state,   challenges, and perspectives. Microbial Cell Factories, 10, 99.   (2016 IF=3.681)