Jing Wu

By: Source: Date：2018-11-12 Updating:2018-11-12 View：

Professor

Tel: 0510-85327802

Email: jingwu@jiangnan.edu.cn

Website: http://letbe.jiangnan.edu.cn/

Education & Experience

2007 – Present Professor, Jiangnan University, State Key Laboratory

of Food Science and Technology

2006 – Present Professor, Jiangnan University, School of

Biotechnology

2005 – 2006 Research Investigator, University of Michigan

2001 – 2005 Postdoctoral Fellow, University of Michigan

1997 – 2001 Ph.D., China Pharmaceutical University

1993 – 2001 Lecturer, China Pharmaceutical University

1990 – 1992 M.E., Wuxi Institute of Light Industry

1986 – 1990 B.E., Wuxi Institute of Light Industry

Research Fields

Our Laboratory is committed to exploring new types of fermentation products and functional food using technology of Molecular Biology, Genetic Engineering, Fermentation Engineering, and Enzymatic Engineering. The specific research area including: enzyme discovery and gene identification, molecular design and reconstruction of enzymes, efficient expression system development, fermentation process optimization and control, as well as enzyme catalysis and conversion.

Selected Publications

1. Xiumei Tao, Tian Wang, Lingqia Su*, Jing Wu*, Enhanced 2-O-α-D-glucopyranosyl-L-ascorbic acid synthesis through lterative saturation mutagenesis of acceptor subsite residues in Bacillus stearothermophilus NO₂ cyclodextrin glycosyltransferase, Journal of Agricultural and Food Chemistry, 2018, 66(34):9052-9060.

2. Kang Zhang, Lingqia Su, Xuguo Duan, Lina Liu, Jing Wu*, High-level extracellular protein production in Bacillus subtilis using an optimized dual-promoter expression system, Microbial Cell Factories, 2017, 16(1): 32.

3. Lingqia Su, Ruoyu Hong, Xiaojie Guo, Jing Wu*, Yongmei Xia. Short-chain aliphatic ester synthesis using Thermobifida fusca cutinase, Food Chemistry, 2016, 206, 131–136
4. Lei Wang, Xuguo Duan, Jing Wu*, Enhancing the α-cyclodextrin specificity of cyclodextrin glycosyltransferase from Paenibacillus macerans by mutagenesis masking subsite-7, Applied and Environmental Microbiology, 2016, 82(8): 2247-2255.

5. Chun Zou, Xuguo Duan, Jing Wu*, Magnesium ions increase the activity of Bacillus deramificans pullulanase expressed by Brevibacillus choshinensis, Applied Microbiology and Biotechnology, 2016, 100(16): 7115-7123.

6. Xuguo Duan, Chun Zou, Jing Wu*, Triton X-100 enhances the solubility and secretion ratio of aggregation-prone pullulanase produced in Escherichia coli, Bioresource Technology, 2015, 194: 137-143.

7. Xuguo Duan, Jing Wu*, Enhancing the secretion efficiency and thermostability of Bacillus deramificans pullulanase mutant D437H/D503Y by N-terminal domain truncation, Applied and Environmental Microbiology, 2015, 81(6): 1926-1931.

8. Chun Zou, Xuguo Duan, Jing Wu*, Enhanced extracellular production of recombinant Bacillus deramificans pullulanase in Escherichia coli through induction mode optimization and a glycine feeding strategy, Bioresource Technology, 2014, 172: 174-179.

9. Zhaofeng Li, Sheng Chen, Zhengbiao Gu, Jian Chen, Jing Wu*, Alpha- cyclodextrin: enzymatic production and food applications, Trends in Food Science and Technology, 2014, 35(2): 151-160.

10. Sheng Chen, Lingqia Su, Jing Wu*, Jian Chen, Cutinase: characteristics, preparation, and application, Biotechnology Advances, 2013, 31(8): 1754-1767.

Patents

1. Jing Wu, Lingqia Su, Kailin Yao. A Maltooligosyl trehalose synthase mutant and its application. US15820487.

2. Jing Wu, Lingqia Su, Ruoyu Hong. Methods for deinking wastepaper by combined use of cutinase and chemical reagents.US15051677

3. Jing Wu, Lingqia Su, and Jian Chen. A method for enhancing extracellular secretion of recombinant proteins in Escherichia coli by Co-expressing Thermobifida Fusca cutinase,US 9109212.

4. Jing Wu, Lei Wang, Dan Wu, and Jian Chen. A method for producing γ-cyclodextrin by simultaneous use of γ- cyclodextrin glycosyltransferase and isoamylase, US8871473B2.

5. Jian Chen, Jing Wu, Dan Wu, Lei Wang. Cutinase producing genetically engineered microorganism and use thereof, US8785169B2.

6. Jing Wu, Xuguo Duan, Hongyan Ran. The genic engineering strain for high yield of isoamylase and its fermentation technology, ZL201510134393.X.

7. Jing Wu, Sheng Chen, Yulu Yang. Methods for producing coupling sugar by use of cyclomaltodextrin glucanotransferase, ZL201410677531.4.

8. Jing Wu, Xuguo Duan, Sheng Chen. SIase mutant with high thermal stability and high catalytic efficiency, ZL201510146238.X.

9. Jing Wu, Lingqia Su, Sheng Chen, Yanjun Xiong. The cyclomaltodextrin glucanotransferase mutants with high conversion rate of AA-2G. ZL201410779194.X

10. Jing Wu, Xuguo Duan, Huachen Sun. Maltogenic Amylase Mutants and its Preparation Method. ZL201510025813.0

Research project

1. National Natural Science Foundation of China (31730067).

2. National Science Fund for Distinguished Young Scholars (31425020).

3. Production and Research Prospective Joint Research Project of Jiangsu Province

(BY2015019-32).

4. National Natural Science Foundation of China (31271813).

5. National Basic Research Program of China (973 Program) (32013CB733902).

6. National High Technology Research and Development Program("863"Program) of China (2012AA02150101).

7. Industrial Support Project in Jiangsu Province (BE2012018).

8. National Natural Science Foundation of China (30970057).

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