Yu Deng

Professor 

Tel: +8613665117395

Email: dengyu@jiangnan.edu.cn

Web: 

2015 – present         Professor, Jiangnan University

2013 – 2014            Assistant Professor, Kansas State University

2011 – 2013            Postdoctoral Fellow, Dartmouth College

2007– 2011          Ph.D., Virginia Commonwealth University

2005 – 2007             M.Sc. Jiangnan University

2001 – 2005             B.Sc., Jiangnan University

1) Biosynthesis of dicarboxylic acids such as adipic acid and glutaric acid by metabolic engineering;

2) Rational design of promoter and RBS to control the dynamic range of biosensors;

3) Design novel pathways for synthesizing unnatural organic compounds;

4) Development of novel biological tools for solving complicated problems occurring in synthetic biology.

1. Mei Zhao, Guohui Li, Yu Deng*, Engineering Escherichia coli for glutarate production as the C5 platform backbone, Applied and Environmental Microbiology, 2018, 84:e00814-18. (IF 3.633).

2. Na Chen, Jingya Wang, Yunying Zhao and Yu Deng*. Metabolic engineering of Saccharomyces cerevisiae for efficient production of glucaric acid at high titer, Microbial Cell factories, 2018, 17:67 (IF =3.831)

3. Mei Zhao, Dixuan Huang, Xiaojuan Zhang, Mattheos A.G. Koffas, Jingwen Zhou and Yu Deng*. Metabolic engineering of Escherichia coli for producing adipic acid through the reverse adipate-degradation pathway, Metabolic Engineering, 2018, 47:254-262. (IF =7.674)

4. Yu Deng*, Ning Ma, Kangjia Zhu, Xuetuan Wei*, Yunying Zhao, Balancing the carbon flux distributions between the TCA cycle and glyoxylate shunt to produce glycolate at high yield and titer in Escherichia coli, Metabolic Engineering, 2018, 46: 28-34. (IF =7.674)

5. Yu Deng*, Xi Zhang, Xiaojuan Zhang, Recent advances in genetic modification systems for Actinobacteria, Applied Microbiology and Biotechnology, 2017, 101(6):2217-2226(IF=3.340).

6. Yu Deng*, Jia Lin, Yin Mao & Xiaojuan Zhang，Systematic analysis of an evolved Thermobifida fusca muC producing malic acid on organic and inorganic nitrogen sources, Scientific Reports, 2016, 6 (IF=4.122).

7. Yu Deng, Mingxue Sun , Sha Xu and Jingwen Zhou, Enhanced (S)-linalool production by fusion expression of farnesyl diphosphate synthase and linalool synthase in Saccharomyces cerevisiae, Journal of Applied Microbiology, 2016, 121, 187-195 (IF=2.160).

8. Yu Deng*, Yin Mao and Xiaojuan Zhang, Metabolic Engineering of a laboratory-evolved Thermobifida fusca muC strain for malic acid production on cellulose and minimal treated lignocellulosic biomass. Biotechnology Progress, 2016, 32:14-20. (IF= 1.947)

9. Yu Deng*, Yin Mao and Xiaojuan Zhang, Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. Journal of Biotechnology, 2015, 216:151–157. (IF= 2.533)

10. Yu Deng*, Li Zhou Ma and Yin Mao, Biological production of adipic acid from renewable substrates: current and future methods. Biochemical Engineering Journal, 2016, 105:16–26. (IF=3.226)

11. Yu Deng*, Yin Mao and Xiaojuan Zhang, Metabolic Engineering of E. coli for Efficient Production of Glycolic Acid from Glucose, Biochemical Engineering Journal, 2015, 103: 256-262. (IF=3.226)

12. Yu Deng*, Adam Fisher and Stephen Fong, Systematic analysis of intracellular mechanisms of propanol production in the engineered Thermobifida fusca B6 strain. Applied Microbiology and Biotechnology, 2015, 99: 8089-8100. (IF=3.340)

13. Yu Deng* and Yin Mao, Production of adipic acid by the native-occurring pathway in Thermobifida fusca B6, Journal of Applied Microbiology, 2015, 119:1057–1063. (IF =2.160)

14. Yu Deng* and Xiaojuan Zhang, DtxR, an iron-dependent transcriptional repressor that regulates the expression of siderophore gene clusters in Thermobifida fusca, FEMS Microbiology Letters, 2015, 362: 1–6. (IF=1.735)

15. Yu Deng, Daniel G. Olson, Jilai Zhou, Christopher D. Herring, Arthur J. Shaw, Lee R. Lynd. Redirecting carbon flux through exogenous pyruvate kinase to achieve high ethanol yields in Clostridium thermocellum. Metabolic Engineering, 2013,15:151-158. (IF=7.674)